Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Catalytically Perfect Enzymes

Catalytically Perfect Enzymes

The theory of catalytically perfect enzymes was first proposed by W.J. Albery and J. R. Knowles in 1976. These enzymes catalyze biochemical reactions at high-speed. Their catalytic efficiency values range from 108-109 M-1s-1. These enzymes are also called 'diffusion-controlled' as the only rate-limiting step in the catalysis is that of the substrate diffusion into the active site. Examples include triose phosphate isomerase, fumarase, and superoxide dismutase.

Most enzymes...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Electrically functionalized body surface for deep-tissue bioelectrical recording.

Nature biomedical engineering·2026

Same author

Cation-Limited Hydroxide Anion Diffusion Drives Asymmetric Hydrogen Kinetics on Transition-Metal Decorated Platinum Surface.

Journal of the American Chemical Society·2026

Same author

Complete Phase Transformation of Ir Nanowire Network into Defect-Rich Oxide Catalyst for High-Performance PEM Water Electrolysis.

Advanced materials (Deerfield Beach, Fla.)·2026

Same author

Heterogenization of Fe<sup>3+</sup> Ions on Chiral Carbon Dots With Enhanced Activity and Stability in DOPA Oxidation.

Small (Weinheim an der Bergstrasse, Germany)·2026

Same author

Tracking the Evolution of Iridium Nanocatalysts During Acidic Oxygen Evolution Reaction by Substrate-Stabilized Identical-Location Transmission Electron Microscopy.

Small methods·2026

Same author

A Three-Component Strategy for Synthesizing High-Entropy Alloy Nanoparticles with High-Index Facets.

Journal of the American Chemical Society·2026

Same journal

Erratum for the Research Article "Assessing the health risks of rice cadmium content standards in China" by H. Chu <i>et al</i>.

Science advances·2026

Same journal

Erratum for the Research Article "Developmental regulation of Erk signaling by mitotic kinases" by F. Chen <i>et al</i>.

Science advances·2026

Same journal

Magnetically levitated metasurface enabling tangible and bidirectional human-machine interaction.

Science advances·2026

Same journal

A general photoinduced manganese-catalyzed platform for the sequential difunctionalization of [1.1.1]propellane.

Science advances·2026

Same journal

Turning sound and force into light with AlN:Mn<sup>2+</sup> mechanoluminescence.

Science advances·2026

Same journal

Extreme dominance of Earth-origin heavy ions in the intense ring current near the Earth during the May 2024 super geomagnetic storm.

Science advances·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 14, 2025

Preparation and 3D Tracking of Catalytic Swimming Devices

Preparation and 3D Tracking of Catalytic Swimming Devices

Published on: July 1, 2016

Surface molecular pump enables ultrahigh catalyst activity.

Jin Huang¹, Bosi Peng^1,2, Cheng Zhu³

¹Department of Materials Science and Engineering, University of California, Los Angeles, CA 90095, USA.

Science Advances

|September 6, 2024

Summary

This summary is machine-generated.

Dimethylformamide acts as a surface molecular pump, enhancing oxygen reduction reaction activity by 2-3 times. This novel approach boosts electrocatalyst performance for renewable energy applications.

More Related Videos

Millifluidics for Chemical Synthesis and Time-resolved Mechanistic Studies

Millifluidics for Chemical Synthesis and Time-resolved Mechanistic Studies

Published on: November 27, 2013

Multiscale Sampling of a Heterogeneous Water/Metal Catalyst Interface using Density Functional Theory and Force-Field Molecular Dynamics

Multiscale Sampling of a Heterogeneous Water/Metal Catalyst Interface using Density Functional Theory and Force-Field Molecular Dynamics

Published on: April 12, 2019

Related Experiment Videos

Last Updated: Jun 14, 2025

Preparation and 3D Tracking of Catalytic Swimming Devices

Preparation and 3D Tracking of Catalytic Swimming Devices

Published on: July 1, 2016

Millifluidics for Chemical Synthesis and Time-resolved Mechanistic Studies

Millifluidics for Chemical Synthesis and Time-resolved Mechanistic Studies

Published on: November 27, 2013

Multiscale Sampling of a Heterogeneous Water/Metal Catalyst Interface using Density Functional Theory and Force-Field Molecular Dynamics

Multiscale Sampling of a Heterogeneous Water/Metal Catalyst Interface using Density Functional Theory and Force-Field Molecular Dynamics

Published on: April 12, 2019

Area of Science:

Materials Science
Electrochemistry
Computational Chemistry

Background:

Electrocatalyst performance is crucial for renewable energy technologies.
The catalyst-electrolyte interface remains underexplored for optimizing microkinetic processes.
The Sabatier principle guides catalyst design but overlooks interfacial effects.

Purpose of the Study:

To investigate the role of the catalyst-electrolyte interface in electrocatalysis.
To explore dimethylformamide (DMF) as a surface molecular pump.
To enhance the activity of oxygen reduction reaction (ORR) electrocatalysts.

Main Methods:

Experimental designs combined with molecular dynamics simulations.
Explicit solvent simulations for high accuracy.
Characterization of platinum-alloy catalysts, including a model PtCuNi catalyst.

Main Results:

Dimethylformamide was demonstrated to facilitate oxygen entrapment and water outflux.
DMF disrupts interfacial hydrogen bonds, enhancing ORR activity by 2-3 times.
An optimal PtCuNi catalyst achieved a record specific activity of 21.8 ± 2.1 mA/cm² and mass activity of 10.7 ± 1.1 A/mg_Pt.

Conclusions:

The catalyst-electrolyte interface offers a promising avenue for improving electrocatalyst performance.
Dimethylformamide serves as an effective surface molecular pump, boosting ORR kinetics.
This strategy is general for platinum-alloy catalysts, paving the way for next-generation electrocatalysts.