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Updated: Jun 13, 2025
A Microwave-Assisted Direct Heteroarylation of Ketones Using Transition Metal Catalysis
Published on: February 16, 2020
Samarium diiodide/samarium-mediated direct deoxygenative hydroborylation of ketones with hydroborane esters
Yongqi Liang1, Yilin Ma1, Wei Zhou1
1Department of Chemistry, Shanghai University, 99 Shangda Road, Shanghai 200444, China. liuchengwei@shu.edu.cn.
Abstract:
A direct deoxygenative hydroborylation of ketones with hydroborane ester promoted by a combination of samarium diiodide, samarium and nickel has been developed. In this method, secondary alkyl borate esters are synthesized from unactivated ketones with hydroborane esters in one step. A broad substrate scope and excellent selectivity toward CO cleavage has been demonstrated. This approach represents a general method for the construction of versatile secondary alkyl borate esters from unactivated ketones.
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