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Visualization of SARS-CoV-2 using Immuno RNA-Fluorescence In Situ Hybridization
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Coronavirus Anatomy and Its Analytical Approaches for Targeting COVID-19
Santheraleka Ramanathan1, M B Malarvili2, Subash C B Gopinath3,4,5
1School of Biomedical Engineering, Universiti Teknologi Malaysia, UTM, 81310, Skudai, Johor, Malaysia.
Advances in Experimental Medicine and Biology
|September 16, 2024
Summary
The Coronavirus 2019 (COVID-19) pandemic spurred research into diagnostic and therapeutic tools. This chapter reviews molecular techniques for COVID-19 prognosis, discussing available methods and their limitations.
Area of Science:
- Virology
- Epidemiology
- Molecular Diagnostics
Background:
- The global Coronavirus 2019 (COVID-19) pandemic has necessitated rapid advancements in diagnostics and therapeutics.
- Emerging variants of SARS-CoV-2 present ongoing challenges for effective treatment and control.
- Understanding viral anatomy and dissemination is crucial for public health strategies and epidemic prediction.
Purpose of the Study:
- To discuss the significance of molecular techniques in developing prognostic analytical methods for COVID-19.
- To evaluate the advantages and limitations of current diagnostic and therapeutic approaches for COVID-19.
Main Methods:
- Review of molecular techniques, including polymerase chain reaction (PCR) and antigen rapid tests.
- Analysis of the role of molecular diagnostics in tracking the COVID-19 epidemic.
- Examination of the scientific literature on antiviral therapies and vaccine development.
Main Results:
- Widespread adoption of PCR and antigen tests has increased testing capacity.
- Molecular techniques are vital for prognostic analysis and understanding COVID-19 progression.
- Challenges remain in developing ideal diagnostic and therapeutic tools due to viral evolution.
Conclusions:
- Molecular techniques offer significant potential for prognostic analysis of COVID-19.
- A comprehensive understanding of viral characteristics and spread is essential for effective pandemic response.
- Continued research is needed to overcome limitations and develop superior diagnostic and therapeutic solutions for COVID-19.
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