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Updated: Jun 12, 2025

Closure of a Patent Foramen Ovale PFO: An Intervention Sequence
Published on: December 23, 2022
Practical Aspects of Patent Foramen Ovale Closure: Ultrasound and Fluoroscopic Guidance
Kerstin Piayda1, Stefan Bertog2, Mackenzie Mbai3
1Cardiovascular Center Frankfurt, Frankfurt, Germany; Department of Cardiology and Vascular Medicine, University Hospital Gießen and Marburg, Gießen, Germany.
Abstract:
Percutaneous PFO closure is a well-established medical procedure to mitigate paradoxic embolism and the future risk of stroke in a well-selected patient clientele. When it comes to procedural guidance during PFO closure, various modalities exist, each with its own advantages and disadvantages. Guidance by transesophageal echocardiography (in combination with fluoroscopy) offers high-resolution 2D/3D imaging, however, it requires the presence of a peri-interventional imager and conscious sedation (or endotracheal intubation). Intracardiac echocardiography and fluoroscopy guidance can be performed by a single operator and omits the need for conscious sedation (or endotracheal intubation).
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