The Use of Focused Ultrasound Ablation for Movement Disorders

Focused ultrasound ablation achieves selective thermal lesioning of the thalamic and basal ganglia targets using real-time MR imaging guidance. It is US Food and Drug Administration-approved to treat essential tremor and Parkinson's disease tremor, fluctuations, and dyskinesias. Patients often seek focused ultrasound treatment because symptom relief is immediate, and hardware implantation is not required. This review summarizes the current and potential future application of focused ultrasound ablation to treat movement disorders. We also discuss the ongoing research optimizing the technique of focused ultrasound ablation to improve long-term efficacy and minimize the risk of side effects.