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Related Concept Videos

Forced Transdifferentiation01:28

Forced Transdifferentiation

Transdifferentiation, also known as lineage reprogramming, was first discovered by Selman and Kafatos in 1974 in silkmoths. They observed that the moths’ cuticle-producing cells transformed into salt-producing cells. Many such cases of natural transdifferentiation occur in organisms. In humans, pancreatic alpha cells can become beta cells. In newts, the loss of the eye’s lens causes the pigmented epithelial cells to transdifferentiate into the lens cells.
Artificial transdifferentiation occurs...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Development of the Sexual Organs in the Embryo and Fetus01:15

Development of the Sexual Organs in the Embryo and Fetus

Development of the reproductive organs in an embryo starts from a bipotential state. This means the early embryo can develop either male or female reproductive organs. The formation of these organs begins with the growth of gonadal ridges that arise from the intermediate mesoderm during the fifth week of development.
Near the gonadal ridges, two duct systems are present: the mesonephric ducts (Wolffian ducts) and paramesonephric ducts (Müllerian ducts). These ducts form the basis for the male...

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Autogenic Molar Transplantation of Third Molar with Complete Root Formation Versus Incomplete Root Formation: A

Ankita Dixit1, Rajbir K Randhawa2, Gagandeep S Randhawa2

  • 1Department of Pedodontics and Preventive Dentistry, Goenka Research Institute of Dental Science, India.

Journal of Pharmacy & Bioallied Sciences
|September 30, 2024
PubMed
Summary

Tooth autotransplantation is a viable option for replacing non-restorable molars, regardless of root development stage. This procedure shows high success rates, offering a beneficial alternative for molar replacement.

Keywords:
Autotransplantationsurgerythird molartransplantation

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Area of Science:

  • Oral surgery
  • Dental implantology
  • Regenerative dentistry

Background:

  • Non-restorable molars often require extraction, leading to functional and aesthetic deficits.
  • Autotransplantation offers a biological alternative to conventional prosthetic or implant rehabilitation.

Purpose of the Study:

  • To evaluate and compare the efficacy of autotransplantation for molars with complete and incomplete root formation.
  • To assess the success rate of replacing non-restorable molars using autotransplantation.

Main Methods:

  • Twenty patients with non-restorable molars underwent autotransplantation of third molars.
  • Patients were divided into two groups based on complete or incomplete root formation of the transplanted tooth.
  • Surgical extraction and atraumatic reimplantation into the extraction socket were performed.

Main Results:

  • A 95% success rate was observed in 19 out of 20 autotransplanted molars after a 6-month follow-up.
  • One transplant failed due to mobility, resulting in a 5% failure rate.
  • Clinical and radiographic evaluations confirmed the viability of the transplanted teeth.

Conclusions:

  • Autotransplantation is a highly effective procedure for replacing non-restorable molars.
  • The success of molar autotransplantation is not influenced by the degree of root formation (complete or incomplete).
  • Autotransplantation presents numerous benefits compared to alternative treatment modalities.