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Investigating the Effects of Various Root Canal Irrigation Solutions on Tissue Dissolution and Microbial Control
Ashima Jakhar1, Anjali Shrivastava Vats2, Simarjeev Singh3
1Bharati Vidyapeeth Dental College and Hospital, Navi Mumbai, Maharashtra, India.
Journal of Pharmacy & Bioallied Sciences
|September 30, 2024
Summary
Sodium hypochlorite (NaOCl) demonstrated superior antimicrobial reduction and pulp tissue dissolution compared to other irrigants. This finding highlights NaOCl as a highly effective agent in endodontic procedures.
Area of Science:
- Endodontics
- Dental materials science
- Microbiology
Background:
- Successful root canal irrigation requires both mechanical cleaning and effective tissue dissolution.
- Ideal irrigants possess strong antibacterial properties without periapical toxicity and enhance pulp tissue removal.
Purpose of the Study:
- To compare the antibacterial efficacy and pulp tissue dissolving capacity of various endodontic irrigants.
Main Methods:
- 240 human premolar teeth were used.
- Colony-forming unit (CFU) counts assessed antibacterial activity.
- Pulp tissue dissolution was evaluated after mechanical disruption.
Main Results:
- Sodium hypochlorite (NaOCl) resulted in 0.00 ± 0.00 log CFU mL⁻¹ bacterial count.
- Super-oxidized water showed 0.21 ± 0.52 log CFU mL⁻¹.
- Aqueous ozone achieved 0.92 ± 0.89 log CFU mL⁻¹.
Conclusions:
- NaOCl exhibited the highest antimicrobial reduction.
- NaOCl demonstrated the most significant pulp tissue dissolution capabilities.
- The study identifies NaOCl as a leading irrigant for endodontic treatment.
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