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Updated: Jun 10, 2025

The Bioconjugation and Radiosynthesis of 89Zr-DFO-labeled Antibodies
Published on: February 12, 2015
Alpha-particles induced reactions on natZr as a pathway of medical 90Nb production
R A Aliev1, E V Artiushova1, A N Moiseeva1
1National Research Centre "Kurchatov Institute", Moscow, Russian Federation.
Abstract:
Reactions on natZr induced by alpha-particles with energies up to 60 MeV were studied by stacked foils method. Production cross-sections for zirconium (88,89,95Zr), niobium (90,92m,95m,95,96Nb) and molybdenum (90,93m,99Mo) radionuclides were determined and thick target yields were calculated. The possibility of obtaining 90Nb through the intermediate formation of 90Mo is discussed. It is possible to obtain 19.6 MBq/(μA·h) 90Mo upon saturation, that leads to 4 MBq/(μA·h) 90Nb after decay.
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