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Central Nervous System Imaging in Rheumatic Diseases.

Shervin Badihian1, Matthew P Kiczek2, Rula A Hajj-Ali3

  • 1Department of Neurology, Neurological Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

Rheumatic Diseases Clinics of North America
|October 17, 2024
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Summary

Rheumatic diseases can affect the central nervous system (CNS), causing symptoms like strokes, seizures, and meningitis. Neuroimaging is crucial for diagnosing these neurological complications in rheumatic patients.

Keywords:
Central nervous systemImagingNeuroimagingRheumatic diseasesSystemic lupus erythematosusVasculitis

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Area of Science:

  • Neurology
  • Rheumatology
  • Neuroimaging

Background:

  • Central nervous system (CNS) involvement is a recognized complication in various rheumatic diseases.
  • Neurological manifestations can precede or accompany systemic symptoms of rheumatic conditions.

Purpose of the Study:

  • To review rheumatic diseases associated with CNS manifestations.
  • To detail the neuroimaging findings in patients with rheumatic diseases and CNS involvement.

Main Methods:

  • Literature review of rheumatic diseases and their CNS manifestations.
  • Analysis of neuroimaging findings reported in affected individuals.

Main Results:

  • Common CNS manifestations include cerebrovascular events, seizures, headaches, demyelinating lesions, and meningeal disease.
  • CNS disease can be the initial presentation of a rheumatic disease.

Conclusions:

  • Recognizing CNS manifestations is vital for diagnosing rheumatic diseases.
  • Neuroimaging plays a key role in identifying and characterizing CNS involvement in rheumatic conditions.