REGULATION OF SPONTANEOUS ELECTRICAL ACTIVITY IN THE ORGANS OF RE-PRODUCTIVE SYSTEM BY OXYTOCIN
K Kazaryan1, N Hunanyan2, M Danielyan3
11Laboratory of Smooth Muscle Physiology, Orbeli Institute of Physiology, Yerevan, Armenia.
Abstract:
The influence of oxytocin on spontaneous electrical activity of the ovarian horn areas as well as the uterine corpus has been studied. Analysis of the main characteristics of activity parameters (amplitude of action potentials, spike generation frequency and total duration of bursts in 1 minute time frame) revealed some notable differences between above mentioned areas. In norm, the highest values of automatism indicators were noted for the left horn. Oxytocin, however, significantly enhances all three parameters. Under its influence, the indicators of the right horn predominate over the values of their own norm, thus emerging among all rhythmogenic loci. Perhaps oxytocin contributes to the activation not only of both fallopian tubes but also of the uterine corpus itself, facilitating the regulation of activity in all three areas.
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