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INPATIENT REHABILITATION AND FUNCTIONAL OUTCOME OF A CASE OF ANTI-SRP IMMUNE-MEDIATED NECROTIZING MYOPATHY
Nicole Chen1, Khin Yamin Thein1, San San Tay1
1From the Department of Rehabilitation Medicine, Changi General Hospital, Singapore.
Journal of Rehabilitation Medicine. Clinical Communications
|October 24, 2024
Summary
This case study shows that a structured rehabilitation program, including robot-assisted gait training, significantly improved function in a patient with anti-signal recognition particle (anti-SRP) necrotizing myopathy. This approach offers a promising avenue for managing this rare autoimmune condition.
Area of Science:
- Neurology
- Immunology
- Rehabilitation Medicine
Background:
- Immune-mediated necrotizing myopathy (IMNM) associated with anti-signal recognition particle (anti-SRP) antibodies is a rare autoimmune disorder causing severe muscle weakness and disability.
- Current literature lacks established rehabilitation guidelines for patients with anti-SRP IMNM, despite recommendations for general myositis.
- Patients often experience significant functional impairment, even after immunosuppressive therapy.
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