Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Gallbladder

Gallbladder

The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...

Diseases of the Liver and Gallbladder

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Multidisciplinary clinics in cancer-models, metrics, and meaning: a review.

The oncologist·2026

Same author

ASO Visual Abstract: Assessing Clinical Factors and Communication Barriers Impacting Postoperative Regret in Patients with Pancreatic Cancer.

Annals of surgical oncology·2026

Same author

Robotic-Assisted Retroperitoneal Sarcoma Resection with Left Renal Vein Reconstruction with Bovine Pericardium.

Annals of surgical oncology·2026

Same author

Assessing Clinical Factors and Communication Barriers Impacting Postoperative Regret in Patients with Pancreatic Cancer.

Annals of surgical oncology·2025

Same author

Addressing the high rates of pregnancy complications and infertility among female surgeons: What should we do about it?

American journal of surgery·2025

Same author

Intraoperative high dose dexamethasone is associated with clinically relevant postoperative pancreatic fistula: a retrospective cohort study.

HPB : the official journal of the International Hepato Pancreato Biliary Association·2025

Same journal

Social Determinants of Health, Health Disparities, and Surgical Equity.

The Surgical clinics of North America·2026

Same journal

Beyond the Scalpel's Reach.

The Surgical clinics of North America·2026

Same journal

Stepwise Solutions-Society.

The Surgical clinics of North America·2026

Same journal

Stepwise Solutions-Hospitals.

The Surgical clinics of North America·2026

Same journal

Stepwise Solutions for Providers.

The Surgical clinics of North America·2026

Same journal

Stepwise Solutions-Patients Social Determinants of Health, Health Disparities, and Surgical Equity.

The Surgical clinics of North America·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 9, 2025

Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb

Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb

Published on: January 17, 2025

Gallbladder Cancer.

Giacomo C Waller¹, Umut Sarpel²

¹Division of Surgical Oncology, Department of Surgery, Icahn School of Medicine at Mount Sinai, 5 East 98th Street, Suite B17, Box #1259, New York, NY 10029-6574, USA. Electronic address: https://twitter.com/gwallermd.

The Surgical Clinics of North America

|October 24, 2024

Summary

This summary is machine-generated.

Gallbladder cancer, a common biliary malignancy, has seen improved outcomes due to surgical and systemic therapy advances. Early detection and staging are crucial for better prognosis in this often advanced-stage disease.

Keywords:

Extended cholecystectomy Gallbladder cancer Incidental gallbladder cancer Radical cholecystectomy

More Related Videos

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction

Published on: March 25, 2022

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy

Published on: March 10, 2023

Related Experiment Videos

Last Updated: Jun 9, 2025

Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb

Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb

Published on: January 17, 2025

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction

Published on: March 25, 2022

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy

Published on: March 10, 2023

Area of Science:

Oncology
Gastroenterology
Surgical Oncology

Background:

Gallbladder cancer is the most frequent biliary tract malignancy.
It is often diagnosed incidentally or at advanced stages, historically associated with poor prognosis.
Risk factors include gender, age, gallbladder disease, and polyp size.

Purpose of the Study:

To review the current understanding of gallbladder cancer.
To discuss diagnostic and management strategies.
To highlight prognostic factors and ongoing research.

Main Methods:

Review of existing literature on gallbladder cancer.
Analysis of epidemiological data and risk factors.
Summary of current diagnostic imaging and surgical approaches.
Discussion of systemic therapies and adjuvant/neoadjuvant treatment roles.

Main Results:

Minimally invasive surgery and systemic therapies have improved patient outcomes.
Management typically involves imaging, staging, and potentially radical cholecystectomy with lymphadenectomy.
The role of adjuvant and neoadjuvant therapies is still under investigation.

Conclusions:

Early detection of gallbladder cancer is critical for improving long-term survival.
Prognosis is strongly dependent on the tumor stage at diagnosis.
Ongoing clinical trials aim to further refine treatment strategies.