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Updated: Jun 7, 2025

Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis
Published on: February 28, 2021
Fluoroscopic, Computed Tomographic, and Magnetic Resonance Myelography
Tarik F Massoud1, Bryan A Lanzman2
1Department of Radiology, Division of Neuroimaging and Neurointervention, and Stanford Initiative for Multimodality Neuro-Imaging in Translational Anatomy Research (SIMITAR), Stanford University School of Medicine, Stanford Health Care, Stanford, USA.
Magnetic resonance imaging has limitations, making fluoroscopic and computed tomographic myelography essential for spinal cord imaging. This review covers technical aspects of these procedures and noninvasive MR myelography for cerebrospinal fluid leak diagnosis.
Area of Science:
- Radiology
- Neuroradiology
- Medical Imaging
Background:
- Magnetic resonance (MR) imaging offers advantages but has contraindications and limitations.
- MR imaging has not fully replaced fluoroscopic or computed tomographic (CT) myelography for spinal cord and nerve root visualization.
- Accurate diagnosis and treatment of cerebrospinal fluid leaks have increased interest in image-guided procedures.
Purpose of the Study:
- To review the technical and periprocedural aspects of fluoroscopic and CT myelography.
- To discuss the application of noninvasive MR myelography in specific clinical situations.
Main Methods:
- Review of technical aspects of fluoroscopic myelography.
- Review of technical aspects of CT myelography.
- Discussion of noninvasive MR myelography techniques and applications.
Main Results:
- Fluoroscopic and CT myelography remain valuable for spinal cord and nerve root depiction, especially when MR imaging is contraindicated.
- Noninvasive MR myelography can be useful in certain clinical scenarios for evaluating cerebrospinal fluid leaks.
- Understanding the technical nuances of these myelographic techniques is crucial for effective diagnosis.
Conclusions:
- Fluoroscopic and CT myelography are important complementary tools to MR imaging in neuroradiology.
- Familiarity with myelographic procedures is essential for diagnosing and managing cerebrospinal fluid leaks.
- This review provides insights into the practical aspects of these imaging modalities.
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