[Structure of the centriole complex in mouse hepatocytes in the experimental induction of a G2 block]

In the regenerating liver hepatocytes the centriolar cycle is retarded corresponding to the delay of the nuclear cycle up to the beginning of G2-block. A prolonged staying of cells in the premitotic condition results in the phenomenon that according to their DNA these cells correspond to the G2-period, whereas according to their centriolar complex structure they move into the following G1 and G0-periods, passing mitosis. Thus, in the G2-blocked hepatocytes there is a separation of the nuclear cycle and centriolar cycles. Moreover, during the diping action the centriolar capacity of forming cytoplasmic and mitotic microtubules is suppressed.