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Christian Schmidt Mortensen1, Stine Maria Lund Andersen1, Louise Westerskov Schøsler1

  • 1Afdelingen for Hud- og Kønssygdomme, Aarhus Universitetshospital.

Ugeskrift for Laeger
|November 13, 2024
PubMed
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Majocchi's granuloma, a rare fungal infection, often presents with scaling and pustules. Early diagnosis via clinical, mycological, and histologic examination is key for effective treatment with terbinafine.

Area of Science:

  • Dermatology
  • Mycology
  • Pathology

Background:

  • Majocchi's granuloma is an uncommon deep fungal folliculitis.
  • Predisposing factors include topical steroid use and immunosuppression.

Observation:

  • Clinical presentation includes exanthema with perifollicular nodules, pustules, and peripheral scaling.
  • Diagnosis relies on clinical, mycological, and histologic examination.

Findings:

  • Histologic examination reveals perifollicular granulomatous inflammation.
  • Trichophyton rubrum is the primary causative agent.

Implications:

  • Prompt diagnosis and treatment are crucial for managing Majocchi's granuloma.
  • Combined systemic and topical antifungal therapy, such as terbinafine, is effective.

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