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Updated: Jun 7, 2025

Synthesis of Near-Infrared Emitting Gold Nanoclusters for Biological Applications
Published on: March 22, 2020
Functional utility of gold complexes with phosphorus donor ligands in biological systems
Adedamola S Arojojoye1, Samuel G Awuah1,2,3,4
1Department of Chemistry, University of Kentucky, Lexington KY 40506.
Abstract:
Metallo-phosphines are ubiquitous in organometallic chemistry with widespread applications as catalysts in various chemical transformations, precursors for organic electronics, and chemotherapeutic agents or chemical probes. Here, we provide a comprehensive review of the exploration of the current biological applications of Au complexes bearing phosphine donor ligands. The goal is to deepen our understanding of the synthetic utility and reactivity of Au-phosphine complexes to provide insights that could lead to the design of new molecules and enhance the cross-application or repurposing of these complexes.
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