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Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...

Cancer Therapies

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...

Combination Therapies and Personalized Medicine

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...

Tumor Immunotherapy

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.

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Updated: Jun 7, 2025

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Published on: February 12, 2017

Systemic Therapy for Small Cell Lung Cancer: ASCO Guideline Rapid Recommendation Update.

Gregory P Kalemkerian¹, Humera Khurshid², Nofisat Ismaila³

¹University of Michigan, Ann Arbor, MI.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology

|November 20, 2024

Summary

ASCO Rapid Recommendation Updates provide timely revisions to cancer care guidelines based on new evidence. These updates help healthcare professionals and the public make informed decisions about cancer treatment options.

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Last Updated: Jun 7, 2025

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

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Area of Science:

Oncology
Clinical Practice Guidelines

Background:

ASCO guideline recommendations require updates to reflect new clinical data.
Timely dissemination of updated guidelines is crucial for effective cancer care.

Purpose of the Study:

To highlight revisions to select ASCO guideline recommendations.
To inform health practitioners and the public about the best available cancer care options.

Main Methods:

Evidence reviews are conducted to support guideline revisions.
Updates follow established ASCO Guideline Development processes.

Main Results:

Select ASCO guideline recommendations are revised based on new evidence.
Updated recommendations are disseminated rapidly.

Conclusions:

Rapid Recommendation Updates ensure guidelines remain current with practice-changing data.
These updates support informed decision-making in cancer care.