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Fluid dynamics is the study of fluids in motion. Velocity vectors are often used to illustrate fluid motion in applications like meteorology. For example, wind—the fluid motion of air in the atmosphere—can be represented by vectors indicating the speed and direction of the wind at any given point on a map. Another method for representing fluid motion is a streamline. A streamline represents the path of a small volume of fluid as it flows. When the flow pattern changes with time, the...
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openBF: an open-source finite volume 1D blood flow solver.

I Benemerito1,2, A Melis3, A Wehenkel4

  • 1INSIGNEO Institute for in-silico medicine, University of Sheffield, Sheffield, United Kingdom.

Physiological Measurement
|November 22, 2024
PubMed
Summary
This summary is machine-generated.

openBF is a new open-source computational library for simulating blood flow dynamics in the cardiovascular system. It provides accurate predictions quickly, aiding cardiovascular biomechanics research.

Keywords:
1D modellingcardiovascular systemopen sourcevalidation

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Area of Science:

  • Biomedical Engineering
  • Computational Fluid Dynamics
  • Cardiovascular Physiology

Background:

  • Computational simulations are crucial for obtaining physiological data in cardiovascular biomechanics.
  • Non-invasive measurement limitations necessitate advanced simulation tools.

Purpose of the Study:

  • To introduce openBF, a novel computational library for simulating blood dynamics.
  • To provide an accessible and efficient tool for cardiovascular system modeling.

Main Methods:

  • Utilizes a one-dimensional viscoelastic model for the arterial system.
  • Couples arterial models with zero-dimensional Windkessel models at outlets.
  • Employs the finite-volume method for solving equations, implemented in Julia.

Main Results:

  • openBF demonstrates excellent agreement with existing software across various scales, from single arteries to virtual populations.
  • Achieves low computational times for simulations.
  • Validated through multiscale studies using literature data.

Conclusions:

  • openBF offers accurate blood dynamics predictions in short time frames.
  • The library is easy to install, use, and deploy on multiple platforms.
  • Actively maintained and open-source, fostering community contributions in biomechanics.