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Transcatheter Tricuspid Valve Replacement.
Jörg Hausleiter1, Lukas Stolz2, Philipp Lurz3
1Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.
Journal of the American College of Cardiology
|November 24, 2024
Summary
Transcatheter tricuspid valve replacement (TTVR) offers a new treatment for severe tricuspid regurgitation. This review details TTVR
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Severe tricuspid regurgitation (TR) poses significant challenges, particularly with complex valve morphology.
- Transcatheter tricuspid valve replacement (TTVR) is an emerging therapeutic option for high-risk surgical patients.
- Current treatment strategies for severe TR often involve high surgical risk.
Purpose of the Study:
- To provide a comprehensive consensus on orthotopic TTVR.
- To outline patient selection criteria, procedural techniques, and follow-up protocols for TTVR.
- To serve as a reference for clinicians and researchers in the evolving field of TTVR.
Main Methods:
- Review of current literature and clinical outcomes from initial TTVR studies and compassionate use cases.
- Analysis of data focusing on TTVR effectiveness, safety, and patient quality of life.
- Expert recommendations for periprocedural management, anticoagulation, and long-term follow-up.
Main Results:
- TTVR demonstrates effectiveness in reducing tricuspid regurgitation.
- The procedure promotes reverse right ventricular remodeling.
- Patients undergoing TTVR experience enhanced quality of life.
Conclusions:
- TTVR is a promising intervention for severe tricuspid regurgitation, especially in complex cases.
- Potential complications include conduction disturbances, bleeding, and afterload mismatch.
- Standardized management and follow-up are crucial for successful TTVR outcomes.
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