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Iron Deficiency in Preschool Children with Chronic Rhinitis

Yu-Fang Lo1, Jia-Kan Chang1

  • 1Department of Pediatrics, Cheng Hsin General Hospital, Taipei, Taiwan.

Pediatric Allergy, Immunology, and Pulmonology
|November 27, 2024
PubMed

Insights

Nearly half of preschool children with chronic rhinitis have iron deficiency (ID). Higher neutrophil and monocyte counts were linked to iron deficiency in these children, suggesting an immune system connection.

Area of Science:

  • Pediatric Allergy and Immunology
  • Pediatric Hematology
  • Pediatric Respiratory Medicine

Background:

  • Iron deficiency (ID) is associated with inflammatory conditions.
  • Chronic rhinitis is a common respiratory inflammatory disorder in children.
  • Understanding ID in pediatric chronic rhinitis is crucial.

Purpose of the Study:

  • To determine the prevalence of iron deficiency in preschool children with chronic rhinitis.
  • To investigate the association between iron deficiency and chronic rhinitis in this age group.

Main Methods:

  • A cross-sectional study included 72 children aged 3-7 years with chronic rhinitis.
  • Iron deficiency was defined by transferrin saturation <20% or ferritin <15 ng/mL.
  • Logistic regression analysis identified factors associated with ID.

Main Results:

  • The prevalence of iron deficiency was 47.2% among children with chronic rhinitis.
  • Absolute iron deficiency was found in only 5.9% of affected children.
  • Neutrophils (OR=1.205) and monocytes (OR=1.803) were significantly associated with ID.

Conclusions:

  • A substantial prevalence of iron deficiency exists in preschool children with chronic rhinitis.
  • The association of neutrophils and monocytes with ID suggests innate immunity involvement.
  • Further research into the interplay between iron status and pediatric rhinitis is warranted.

Keywords:
atopychronic rhinitisiron deficiencyiron deficiency anemiapediatrics

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