[Research advances on light-adjustable intraocular lens].

Area of Science:

• Ophthalmology
• Biomedical Engineering
• Materials Science

Background:

• Refractive error significantly impacts visual acuity following cataract surgery.
• Conventional refractive error correction methods are invasive and carry risks of surgical complications.
• Non-invasive techniques for post-cataract surgery refractive error correction are clinically significant.

Purpose of the Study:

• To review advancements in light-adjustable intraocular lenses (IOL).
• To provide insights into ongoing research and clinical applications of adjustable IOL technology.

Main Methods:

• Review of current literature on light-adjustable IOL technologies.
• Categorization of adjustable IOLs based on adjustment mechanisms (UV light, thermomechanical, femtosecond laser, two-photon effects).

Main Results:

• Light-adjustable IOLs enable in vitro dioptric power modification via light exposure.
• Diverse technologies exist, including UV-adjustable, nitinol-based, femtosecond laser-induced, and two-photon effect IOLs.
• These lenses offer a non-invasive method for refractive error correction.

Conclusions:

• Light-adjustable IOLs represent a promising non-invasive approach to refining refractive outcomes post-cataract surgery.
• Continued research and development in this area are crucial for clinical practice.
• The diverse technologies offer tailored solutions for refractive error management.