Related Experiment Video
Updated: Jun 5, 2025
Micro-Computed Tomography Analysis of the Knee in Aged Dunkin-Hartley Guinea Pigs after Intra Articular Injection
Published on: August 2, 2024
Co-occurrence of Pigmented Villonodular Synovitis and Patellar Clunk Syndrome Following Total Knee Arthroplasty: A
José L Ayala-Ortiz1, Chase Hobbs1, John Murphy1
1Orthopaedic Surgery, The University of Alabama at Birmingham, Birmingham, USA.
Abstract:
Pigmented villonodular synovitis (PVNS) is an uncommon hyperproliferative disease of the synovium presenting either as localized or a more aggressive diffuse form. Its occurrence following total knee arthroplasty (TKA) is rare, and its presentation alongside patellar clunk syndrome (PCS) has not been previously reported. We present a case of a 64-year-old female patient diagnosed with diffuse PVNS (D-PVNS) two and half years following TKA, co-occurring with PCS. The diagnosis was initially suspected during a diagnostic arthroscopy for PCS, after which the patient underwent arthroscopic synovectomy and scar excision. Histological analysis of the resected tissue confirmed the diagnosis, revealing inflammatory cells and hemosiderin deposits.
Related Concept Videos
01:23Knee Joint
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
01:10Ankle Joint
01:07Development of the Limb Synovial Joints
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...