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PREVALENCE AND ASSOCIATED FACTORS OF CHOROIDAL CAVERN IN PATIENTS WITH TYPE 2 DIABETES MELLITUS
Lourdes Vidal-Oliver1,2, Sabrina Spissinger2, Elisa Herzig-de Almeida2
1Department of Ophthalmology, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany ; and.
Retina (Philadelphia, Pa.)
|December 9, 2024
Summary
Choroidal caverns (CCs) appear in about a quarter of patients, regardless of Type 2 diabetes (T2DM). The choroidal vascularity index is linked to CCs, suggesting increased metabolic activity in the choroid.
Area of Science:
- Ophthalmology
- Diabetology
- Medical Imaging
Background:
- Choroidal caverns (CCs) are vascular anomalies in the choroid.
- Their prevalence and association with Type 2 diabetes (T2DM) require further investigation.
Purpose of the Study:
- To determine the prevalence of CCs in patients with T2DM.
- To explore the association between CCs and demographic and clinical factors in T2DM patients.
Main Methods:
- A cross-sectional study included T2DM patients and non-diabetic controls.
- Choroidal caverns were identified, and associations with age, sex, diabetic retinopathy, T2DM duration, HbA1c, and choroidal vascularity index were assessed.
Main Results:
- CCs were found in 25% of controls and 28% of T2DM patients without retinopathy, and 9.5% of those with retinopathy.
- CCs were predominantly located in the Sattler layer.
- Choroidal vascularity index was the sole factor independently associated with CC presence (OR 1.37).
Conclusions:
- CCs are present in a significant portion of individuals, irrespective of T2DM status.
- The choroidal vascularity index may serve as a biomarker for CCs, potentially indicating heightened choroidal metabolic activity.
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