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Updated: Jun 4, 2025

Preclinical Cardiac Electrophysiology Assessment by Dual Voltage and Calcium Optical Mapping of Human Organotypic Cardiac Slices
Published on: June 16, 2020
From bits to bedside: entering the age of digital twins in cardiac electrophysiology
Pranav Bhagirath1,2, Marina Strocchi3, Martin J Bishop2
1Department of Cardiology, Amsterdam University Medical Center, Meibergdreef 9, Amsterdam, 1105 AZ, The Netherlands.
Abstract:
This State of the Future Review describes and discusses the potential transformative power of digital twins in cardiac electrophysiology. In this 'big picture' approach, we explore the evolution of mechanistic modelling based digital twins, their current and immediate clinical applications, and envision a future where continuous updates, advanced calibration, and seamless data integration redefine clinical practice of cardiac electrophysiology. Our aim is to inspire researchers and clinicians to embrace the extraordinary possibilities that digital twins offer in the pursuit of precision medicine.
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