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Updated: Jun 3, 2025

Semi-Quantitative Analysis of Peptidoglycan by Liquid Chromatography Mass Spectrometry and Bioinformatics
Published on: October 13, 2020
Analysis of Chemical Components of Penicillium chrysogenum Crude Extract Using Liquid Chromatography Coupled With
1School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, Tianjin, China.
Abstract:
A Chinese isolate of the fungus Penicillium chrysogenum was analyzed using liquid chromatography coupled with Q-Exactive Orbitrap mass spectrometry combined with Global Natural Products Social Networking (GNPS) on culture condition leading to the rapid identification of 20 secondary metabolites. Among them are eight polyketones, two phthalides, six diketopiperazine alkaloids, and others. A meleagrine network was examined and proposed as a promising candidate for new natural products.
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