Hidradenitis Suppurativa and Peripheral Ulcerative Keratitis

Area of Science:

• Ophthalmology
• Dermatology
• Rheumatology

Background:

• Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition.
• Ocular manifestations of HS are uncommon, typically presenting as anterior uveitis.
• Peripheral ulcerative keratitis (PUK) is a severe inflammatory eye condition.

Observation:

• This report details a unique case of PUK in a patient with severe HS.
• Extensive infectious and rheumatological workups were negative.
• This presentation prompted consideration of a potential association between PUK and HS.

Findings:

• The co-occurrence of PUK and HS is exceedingly rare.
• Only six cases of PUK associated with HS have been previously documented.
• This case adds to the limited evidence suggesting a link between HS and PUK.

Implications:

• This case underscores the importance of considering dermatological conditions like HS in the differential diagnosis of PUK.
• Further research may elucidate the underlying mechanisms connecting HS and PUK.
• Recognition of this association can potentially improve patient management and outcomes.