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Wireless Frequency-Multiplexed Acoustic Array-based Acoustofluidics.

Jiali Li1, Luyu Bo1, Teng Li1

  • 1Department of Mechanical Engineering, Virginia Polytechnic Institute and State University, Blacksburg, VA, 24060, USA.

Advanced Materials Technologies
|February 5, 2025
PubMed
Summary
This summary is machine-generated.

This study introduces wireless acoustofluidic chips for on-demand liquid processing and particle manipulation in wearable electronics. These chips enable functions like cell alignment and particle enrichment using wireless power transfer and acoustic waves.

Keywords:
Acoustofluidicsacoustic patterningfrequency-multiplexed acoustic arraylaser Doppler vibrometry

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Area of Science:

  • Acoustofluidics
  • Wireless Power Transfer (WPT)
  • Biomedical Engineering

Background:

  • Acoustofluidics enables on-chip liquid flow and particle manipulation for various applications.
  • Wireless acoustofluidic chips are needed for wearable and embeddable electronics.
  • Existing technologies lack wireless capabilities for on-demand sample processing.

Purpose of the Study:

  • To present wireless acoustofluidic chips for on-demand liquid sample processing and micro/nano-object manipulation.
  • To enable functions such as particle arrangement, cell alignment, fluid streaming, and particle enrichment.
  • To integrate acoustofluidic capabilities into wearable and embeddable electronic systems.

Main Methods:

  • Utilized inductive coupling-based wireless power transfer (WPT) for energy delivery.
  • Employed frequency multiplexing for controlling multiple acoustic waves.
  • Leveraged acoustic radiation and drag forces for particle and fluid manipulation.

Main Results:

  • Demonstrated wireless generation of acoustic waves through various materials (bone, tissue, hand).
  • Successfully arranged nanoparticles into distinct patterns.
  • Achieved cell alignment into parallel pearl chains and enriched in-droplet microparticles.
  • Generated controlled fluid streaming.

Conclusions:

  • Wireless acoustofluidic chips can perform key acoustofluidic functions.
  • This technology facilitates the development of embeddable wireless on-chip flow generators.
  • Enables wearable sensors with liquid processing and implantable devices with flow generation capabilities.