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Case Report: Atypical post-COVID Cogan's syndrome.
Sameh Mezri1,2, Chaima Zitouni1,2, Wafa Sleimi1,2
1University of Tunis El-Manar, Tunis, Tunisia.
This case report details a rare instance of Cogan's syndrome, an autoimmune disorder, presenting with neurological complications after COVID-19 infection. The patient experienced ocular inflammation, hearing loss, and meningitis, highlighting atypical disease progression.
Area of Science:
- Ophthalmology
- Neurology
- Rheumatology
Background:
- Cogan's syndrome is a rare autoimmune disorder featuring ocular inflammation, vestibulocochlear dysfunction, and systemic vasculitis.
- Early diagnosis and treatment are crucial for managing this condition and preventing severe complications.
Observation:
- A 28-year-old female developed keratitis, uveitis, and retinal vasculitis one month post-COVID-19 infection.
- She subsequently experienced vertigo, tinnitus, and sudden hearing loss, consistent with Cogan's disease.
- Neurological involvement manifested as lymphocytic meningitis and elevated intracranial pressure.
Findings:
- Corticosteroid therapy led to ocular symptom regression but not hearing recovery, resulting in complete deafness.
- The patient's neurological symptoms improved with treatment.
- Cochlear implants were successfully implemented.
Implications:
- This case highlights an atypical presentation of Cogan's syndrome with neurological sequelae following COVID-19.
- It underscores the importance of considering Cogan's syndrome in patients with autoimmune manifestations post-viral infections.
- Further research is needed to understand the link between COVID-19 and Cogan's syndrome, especially concerning neurological involvement.
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