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Related Concept Videos

Ultrasound II: Endoscopic Ultrasound and FibroScan01:25

Ultrasound II: Endoscopic Ultrasound and FibroScan

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Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
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The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: 2026 Annual Pediatric Heart Transplantation Report, Trends and Post-transplant Outcomes by Recipient Sex.

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The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: 2026 Adult Heart Transplantation: A Contemporary Analysis of Trends and Outcomes by Recipient Sex.

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OPTN/SRTR 2024 Annual Data Report: Overview of US Solid Organ Transplantation.

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OPTN/SRTR 2024 Annual Data Report: Liver.

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OPTN/SRTR 2024 Annual Data Report: Kidney.

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Alpha-Gal Syndrome: Unrecognized Risks of a Tick-Bite-Associated Allergy in Transplantation and Cellular Therapy.

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Comment on "Role of social determinants and outcomes of patients with alcohol-associated liver disease referred for early liver transplantation: A multicenter analysis".

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Ebola disease caused by Bundibugyo virus, Democratic Republic of the Congo & Uganda.

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Donor Acute Kidney Injury Is Not Associated With Inferior Outcomes After Simultaneous Pancreas-Kidney Transplantation.

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Human Biopsy-Defined IRI-Selective Reperfusion Signature Prioritizes Reperfusion-Timed MEK Inhibition After DCD Liver Transplantation.

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OPERATIONAL TOLERANCE FOLLOWING INTESTINAL TRANSPLANTATION: A CASE REPORT WITH COMPREHENSIVE IMMUNE FOLLOW-UP FROM TRANSPLANT DAY TO THREE YEARS POST-IMMUNOSUPPRESSION WITHDRAWAL.

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Related Experiment Video

Updated: May 28, 2025

Laparoscopic Anatomical Liver Segment VII Resection with Liver Parenchymal Transection Following a Priority Approach
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Laparoscopic Anatomical Liver Segment VII Resection with Liver Parenchymal Transection Following a Priority Approach

Published on: May 23, 2025

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OPTN/SRTR 2023 Annual Data Report: Liver.

Allison J Kwong1, W Ray Kim2, John R Lake3

  • 1Division of Gastroenterology and Hepatology, Stanford University, Stanford, CA.

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
|February 13, 2025
PubMed
Summary
This summary is machine-generated.

In 2023, a record 10,659 liver transplants were performed in the US, driven by expanded donor criteria and new scoring systems. Despite progress, disparities in transplant rates and pretransplant mortality persist between sexes.

Keywords:
Liver transplantationliver donationoutcomeswaiting list

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Area of Science:

  • Hepatology
  • Transplant Surgery
  • Public Health

Background:

  • Liver transplantation is a critical treatment for end-stage liver disease.
  • Donor organ availability and allocation systems significantly impact transplant outcomes.
  • Addressing disparities in access to care is a key challenge in transplantation.

Purpose of the Study:

  • To report the 2023 national liver transplant statistics in the United States.
  • To analyze trends in donor utilization, including Donation after Circulatory Death (DCD) and living donation.
  • To evaluate the impact of updated Model for End-Stage Liver Disease (MELD) 3.0 and Pediatric End-Stage Liver Disease (PELD) scoring systems on transplant equity.

Main Methods:

  • Analysis of national liver transplant data from 2023.
  • Review of donor characteristics, including age and DCD status.
  • Assessment of transplant rates and pretransplant mortality by sex and updated MELD/PELD scores.

Main Results:

  • A record 10,659 liver transplants were performed, with growth attributed to older and DCD donors.
  • The nonuse rate of recovered livers decreased to 9.7%, with 16.7% of recipients accepting DCD livers.
  • The MELD 3.0/PELD update narrowed the sex disparity in deceased donor liver transplant rates, but males still received transplants at higher rates.

Conclusions:

  • The increase in liver transplants highlights advancements in organ recovery and utilization.
  • Updated MELD/PELD scoring systems show promise in reducing sex-based disparities in liver transplant allocation.
  • Continued efforts are needed to address remaining inequities in pretransplant mortality and transplant rates for female candidates.