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An Emerging Prospective of Antipsychotics for Treating Neurodegenerative Disorders
Bhavna Kumar1, Arpita Sahoo1, Manmohan Singhal1
1Faculty of Pharmacy, DIT University, Dehradun, 248009, Uttarakhand, India.
Current Pharmaceutical Design
|February 14, 2025
Summary
Antipsychotics may help manage behavioral symptoms in neurodegenerative disorders like Alzheimer's disease. This review examines their benefits, risks, and the need for personalized, multidisciplinary care.
Area of Science:
- Neurology
- Pharmacology
Background:
- Neurodegenerative disorders involve progressive neuron loss, distinct from toxic/metabolic conditions.
- Clinical presentation includes behavioral and cognitive deficits.
- Current management is challenging, requiring multifaceted strategies.
Purpose of the Study:
- To review the literature on using antipsychotics for neurodegenerative disorders.
- To assess the benefits, risks, and considerations of this treatment approach.
- To discuss personalized and multidisciplinary care strategies.
Main Methods:
- Literature review of existing studies.
- Analysis of antipsychotic use in Alzheimer's and Parkinson's disease.
- Exploration of personalized treatment paradigms.
Main Results:
- Antipsychotics show potential in managing behavioral and psychological symptoms.
- Risks and benefits require careful consideration for each patient.
- Personalized, multidisciplinary approaches are crucial for optimal outcomes.
Conclusions:
- Antipsychotics offer a potential therapeutic avenue for specific symptoms in neurodegenerative diseases.
- Careful patient selection and monitoring are essential.
- Integrating personalized medicine and a team-based approach enhances patient care.
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