Peroral Endoscopic Myotomy (POEM) for Achalasia Cardia: A Report of Two Cases

Achalasia cardia is a motility disorder of the esophagus characterized by a lack of esophageal peristalsis and failure of lower esophageal sphincter opening during swallowing. Symptomatic patients present with a long history of difficulty swallowing, along with chest pain and vomiting. Two male patients, 55 and 24 years old, with proven achalasia cardia by high-resolution esophageal manometry (HRM), underwent a successful peroral endoscopic myotomy (POEM) procedure at our center. This was the first time this procedure was done in Nepal. In this case report, we have demonstrated that a novel third-space procedure like POEM can be safely performed in a resource-limited country.