Related Experiment Video
Updated: May 5, 2026

07:30
Learning Modern Laryngeal Surgery in a Dissection Laboratory
Published on: March 18, 2020
8.8K
Contemporary Surgical Approaches in Managing Laryngeal Chondrosarcoma: A Scoping Review
D Alexander Cronkite1, Clare Moffatt1, Kenric Tam2
1Department of Head & Neck Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
The Laryngoscope
|February 19, 2025
Summary
Surgical management of laryngeal chondrosarcoma varies by subsite. Prioritizing larynx preservation over aggressive resection is key, as extensive surgery does not improve survival rates for this rare laryngeal tumor.
Area of Science:
- Otolaryngology
- Surgical Oncology
- Laryngeal Pathology
Background:
- Chondrosarcoma is a rare malignant cartilage tumor.
- Laryngeal chondrosarcoma presents unique surgical challenges due to the complex anatomy of the larynx.
Purpose of the Study:
- To review and evaluate current surgical management strategies for laryngeal chondrosarcoma.
- To correlate surgical techniques with specific laryngeal subsites affected by chondrosarcoma.
Main Methods:
- Scoping review adhering to Preferred Reporting Items for Systematic Reviews extension for Scoping Reviews (PRISMA-ScR) guidelines.
- Systematic search of PubMed/MEDLINE and EMBASE databases.
- Analysis of 149 unique surgical cases from 41 eligible articles.
Main Results:
- Cricoid chondrosarcoma management involved transoral endoscopic resection (TER) or transcervical laryngeal preservation surgery (TPLS), including cricoidectomy with reconstruction.
- Arytenoid and epiglottic chondrosarcomas were effectively treated with TER.
- Thyroid chondrosarcoma, often affecting the outer cartilage, was amenable to transcervical resection.
Conclusions:
- Surgical trends indicate that aggressive resection and achieving R0 margins do not enhance overall survival for laryngeal chondrosarcoma.
- The current treatment philosophy emphasizes larynx and laryngeal function preservation over radical oncologic resection.

