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Related Concept Videos

Arteries of the Lower Limbs01:24

Arteries of the Lower Limbs

177
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
177
Seizures: Classification01:13

Seizures: Classification

297
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
297
Antiepileptic Drugs: Glutamate Antagonists01:14

Antiepileptic Drugs: Glutamate Antagonists

271
Glutamate is a fundamental neurotransmitter in the central nervous system, playing a vital role in neuronal communication and various cognitive processes. Glutamate stands as the principal excitatory neurotransmitter in the brain. Its presence is crucial for the communication between neurons, underpinning essential processes such as synaptic transmission, neuronal excitability, and plasticity. These functions are vital for higher-order cognitive processes, including learning and memory. The...
271
Electroconvulsive Therapy01:30

Electroconvulsive Therapy

22
Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
22
Antiepileptic Drugs: GABAergic Pathway Potentiators01:18

Antiepileptic Drugs: GABAergic Pathway Potentiators

310
γ-aminobutyric acid or GABA, plays a pivotal role as an inhibitory neurotransmitter in the brain. GABA pathway potentiators, also known as GABAergic drugs, are a class of pharmaceutical agents designed to enhance the functioning of the GABAergic system. These medications primarily treat epilepsy, a neurological disorder characterized by recurrent seizures.
The key GABA pathway potentiators used in epilepsy management are as follows.
Benzodiazepines are a well-known class of drugs used for...
310
Antiepileptic Drugs: Sodium Channel Blockers01:08

Antiepileptic Drugs: Sodium Channel Blockers

352
Antiepileptic drugs are specialized medications that prevent seizures in individuals diagnosed with epilepsy. These drugs primarily function by blocking the movement of sodium ions through channels in the neuronal membrane, inhibiting the repetitive firing of action potentials often associated with seizures.
Sodium channel blockers modulate ion channels, particularly voltage-gated sodium channels. They block only sodium ion movement.
Among the most commonly prescribed antiepileptic drugs are...
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Articles linked to this work by shared authors, journal, and citation graph.

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Revue de l'infirmiere·2026
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Sleep increases firing rate modulation during interictal epileptiform discharges in mesial temporal structures.

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Cyclic Recurrence of Seizures as a Marker for Super-Refractory Status Epilepticus.

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Related Experiment Video

Updated: May 27, 2025

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
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[Epilepsy in adults].

Marine Bourgninaud1, Virginie Lambrecq1

  • 1Centre expert d'épilepsies rares, Hôpital Pitié-Salpêtrière, 47-83 boulevard de l'Hôpital, 75013 Paris, France.

Revue De L'Infirmiere
|February 19, 2025
PubMed
Summary

Epilepsy is a chronic neurological disorder affecting millions worldwide. This review covers its causes, related conditions, and emerging therapeutic strategies for better patient outcomes.

Area of Science:

  • Neurology
  • Chronic Disease Research

Context:

  • Epilepsy is a prevalent neurological condition with diverse clinical presentations.
  • Understanding its chronic nature and varied manifestations is crucial for effective management.

Purpose:

  • To provide a comprehensive overview of epilepsy.
  • To detail the pathophysiology, comorbidities, and novel treatment options for epilepsy.

Summary:

  • This article explores the underlying mechanisms (pathophysiology) of epilepsy.
  • It discusses the common co-occurring conditions (comorbidities) associated with epilepsy.
  • New and emerging treatment strategies for epilepsy are presented.

Impact:

  • Enhances understanding of epilepsy for clinicians and researchers.
Keywords:
comorbiditycomorbiditéepilepsyneuronneuronephysiopathologiephysiopathologytraitementtreatmentépilepsie

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  • Informs the development of improved diagnostic and therapeutic approaches.
  • Aims to improve the quality of life for individuals with epilepsy.