PERFORMANCE OF THE PEGUERO-LO PRESTI CRITERIA FOR THE DIAGNOSIS OF LEFT VENTRICULAR HYPERTROPHY IN PATIENTS WITH...

Many criteria have been developed to predict left ventricular hypertrophy using an electrocardiogram (ECG). However, one major common limitation of all has been their low sensitivity. Recently, a novel criterion has been proposed, which is believed to have higher sensitivity without a compromise in specificity.

Therefore, in our study, we aimed to test this novel ECG criterion prospectively in large, unselected cardiac patients in Ibadan, Nigeria.

Patients who were referred to our echocardiography laboratory due to various aetiologies were prospectively enrolled. The novel Peguero-Lo Presti criterion was assessed along with other established ECG criteria. The left ventricular mass index was calculated using echocardiography. The performance of each index was evaluated.

Overall, 336 patients were included in the final analysis. The mean age was 57.94±14.98 and 178 (53.0%) of them were males. The sensitivity and specificity of the Peguero-Lo Presti criterion were 59% and 66%, respectively. Although the highest sensitivity belonged to the Peguero-Lo Presti criterion, in ROC analysis, it showed modest predictive capability, which was similar to the established Cornell voltage criterion.

Although this novel criterion had higher sensitivity, the overall performance was similar to the current indices. Further adjustments, particularly based on age and body mass index, may yield better results.