Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 23, 2025

Generation of Transgenic Rats using a Lentiviral Vector Approach
09:07

Generation of Transgenic Rats using a Lentiviral Vector Approach

Published on: May 17, 2020

8.6K

Pelvic vasectomy and its protective effects on rat testis function.

Heng Yang1,2, Yujun Chen1, Xiaofeng Cheng3

  • 1Jiangxi Provincial Key Laboratory of Urinary System Diseases, Department of Urology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330006, China.

Basic and Clinical Andrology
|March 7, 2025
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mitophagy in bladder cancer: a double-edged sword in tumor progression and therapy.

Journal of translational medicine·2026
Same author

CaSR regulates SLC26A6 expression via the PKA-FOXO4 signaling axis to promote experimental calcium oxalate kidney stone formation in rats.

Frontiers in cell and developmental biology·2026
Same author

Risk factor analysis for septic shock in female patients after mini-percutaneous nephrolithotripsy.

Translational andrology and urology·2026
Same author

Correction: A novel preoperative risk score for predicting Urosepsis after percutaneous nephrolithotomy: validation and clinical application.

Urolithiasis·2026
Same author

A novel preoperative risk score for predicting Urosepsis after percutaneous nephrolithotomy: validation and clinical application.

Urolithiasis·2025
Same author

METS-IR and SII as mediators in the association between smoking and depressive symptoms: insights from NHANES (2005-2018).

BMC psychiatry·2025
This summary is machine-generated.

A modified vasectomy technique shows better reproductive health outcomes in rats than traditional methods. This new approach reduces tissue damage and oxidative stress, preserving reproductive system function.

Area of Science:

  • Reproductive Biology
  • Urology
  • Andrology

Background:

  • Vasectomy is a common male contraceptive, but surgical techniques impact reproductive health.
  • Existing research indicates varied effects of vasectomy methods on tissue damage, oxidative stress, and endocrine function.
  • Limited data exists on the comprehensive impact of different vasectomy techniques on overall reproductive system function.

Purpose of the Study:

  • To evaluate and compare the effects of two distinct vasectomy techniques on reproductive system parameters in a rat model.
  • To investigate the impact of traditional versus modified vasectomy on epididymal morphology, apoptosis, hormone levels, and oxidative stress.
  • To assess the functional consequences of different vasectomy methods on sexual behavior and anxiety levels.

Main Methods:

Keywords:
Epididymal HistopathologyHormone LevelsImmunohistochemistryModified VasectomyRatsTraditional Vasectomy

More Related Videos

Utero-tubal Embryo Transfer and Vasectomy in the Mouse Model
09:33

Utero-tubal Embryo Transfer and Vasectomy in the Mouse Model

Published on: February 28, 2014

47.6K
A Modified Vessel-Sparing Microsurgical Vasoepididymostomy
04:59

A Modified Vessel-Sparing Microsurgical Vasoepididymostomy

Published on: June 8, 2022

1.8K

Related Experiment Videos

Last Updated: May 23, 2025

Generation of Transgenic Rats using a Lentiviral Vector Approach
09:07

Generation of Transgenic Rats using a Lentiviral Vector Approach

Published on: May 17, 2020

8.6K
Utero-tubal Embryo Transfer and Vasectomy in the Mouse Model
09:33

Utero-tubal Embryo Transfer and Vasectomy in the Mouse Model

Published on: February 28, 2014

47.6K
A Modified Vessel-Sparing Microsurgical Vasoepididymostomy
04:59

A Modified Vessel-Sparing Microsurgical Vasoepididymostomy

Published on: June 8, 2022

1.8K
  • Specific pathogen-free male Sprague-Dawley rats were divided into sham, negative control, traditional vasectomy, and modified vasectomy groups (n=6 per group).
  • Procedures were followed by a three-month recovery period, with subsequent analyses including histology (H&E), immunohistochemistry, TUNL staining for apoptosis, ELISA for hormones and oxidative stress markers, and behavioral tests.
  • Reproductive system parameters, tissue integrity, cellular apoptosis, hormonal balance, oxidative stress, and behavioral outcomes were assessed.

Main Results:

  • The modified vasectomy group demonstrated improved epididymis morphology and significantly reduced apoptosis compared to the traditional vasectomy group.
  • Hormone levels remained stable in the modified vasectomy group, with reduced oxidative stress markers observed.
  • Behavioral assessments indicated preserved sexual activity and reduced anxiety in the modified vasectomy group, correlating with the physiological findings.

Conclusions:

  • Modified vasectomy techniques offer superior protection of reproductive system functionality in rats compared to traditional methods.
  • These advanced techniques effectively minimize tissue damage, cellular apoptosis, and oxidative stress.
  • The findings suggest promising clinical implications for modified vasectomy approaches in maintaining male reproductive health.