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Updated: May 23, 2025

Use of the Scissor-Type Knife During the Peroral Endoscopy Myotomy Procedure for the Treatment of Achalasia
Published on: March 3, 2023
Conservative Management of Delayed Submucosal Bleeding after Per-Oral Endoscopic Myotomy: A Case Report
Martina Marrelli1, Dario Biasutto1, Benedetto Neri1,2
1Therapeutic GI Endoscopy Unit, Fondazione Policlinico Universitario Campus Bio-Medico, University of Rome, Rome, Italy.
Per-Oral Endoscopic Myotomy (POEM) for achalasia can cause delayed bleeding. Conservative management, including LMWH discontinuation, successfully treated a patient with a submucosal hematoma post-POEM.
Area of Science:
- Gastroenterology
- Endoscopic Surgery
Background:
- Per-Oral Endoscopic Myotomy (POEM) is a primary treatment for achalasia.
- Submucosal bleeding or hematoma is a rare complication of POEM, occurring in about 1% of cases.
Purpose of the Study:
- To report a case of delayed bleeding and submucosal hematoma after POEM.
- To evaluate the efficacy of conservative management for this complication.
Main Methods:
- A patient with Type II achalasia underwent POEM.
- Delayed bleeding and submucosal hematoma developed after initiating low molecular weight heparin (LMWH).
- Conservative treatment included fasting, antibiotics, LMWH cessation, and close monitoring.
Main Results:
- The patient presented with chest pain but no active arterial bleeding.
- Urgent endoscopy was avoided.
- Complete resolution of the hematoma occurred within 10 days.
Conclusions:
- Conservative management is safe and effective for delayed submucosal hematomas post-POEM.
- This approach avoids the need for urgent endoscopic intervention in select cases.
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