[Management of peripheral arterial disease. Summary of the new European guidelines]

Lucia Mazzolai1, Adriano Alatri1, Luca Calanca1

  • 1Service d'angiologie, Département cœur-vaisseaux, Centre hospitalier universitaire vaudois, 1011 Lausanne.

Revue Medicale Suisse
|March 20, 2025
PubMed

Insights

New European guidelines offer a comprehensive approach to peripheral arterial disease (PAD) management. They stress risk factor control, early diagnosis via ankle-arm pressure index, and exercise for intermittent claudication, with revascularization as a last resort.

Area of Science:

  • Vascular Medicine
  • Cardiology
  • Public Health

Context:

  • Peripheral arterial disease (PAD) affects a significant portion of the population, increasing cardiovascular risk.
  • Current management strategies require updates to reflect the latest evidence and guidelines.

Purpose:

  • To outline new European guidelines for the comprehensive management of peripheral arterial disease.
  • To emphasize a holistic approach encompassing prevention, diagnosis, treatment, and follow-up.

Summary:

  • Guidelines highlight the critical management of cardiovascular risk factors (smoking, hyperlipidemia, hypertension, diabetes) through lifestyle modifications and pharmacotherapy (statins, antiplatelet agents, anticoagulants).
  • Diagnosis relies on the ankle-arm pressure index and ultrasound as the primary imaging modality.
  • Supervised exercise is the recommended first-line treatment for intermittent claudication, with revascularization reserved for persistent symptoms despite optimal management.

Impact:

  • Provides clinicians with updated, evidence-based recommendations for PAD care.
  • Aims to improve patient outcomes by standardizing prevention, diagnosis, and treatment strategies.
  • Encourages a multidisciplinary approach to managing PAD and its associated cardiovascular risks.

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