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Simple Microneedling Versus Microneedling With Topical Insulin In The Treatment Of Post Acne Atrophic Scars; A Split
Maira Ali1, Najia Ahmed1, Seemab Khan1
1Department of Dermatology, PNS Shifa, Karachi, Pakistan.
Journal of Ayub Medical College, Abbottabad : JAMC
|March 23, 2025
Summary
Microneedling with topical insulin significantly improved acne scars compared to simple microneedling. This combination therapy offers a promising, cost-effective treatment for post-acne scarring.
Area of Science:
- Dermatology
- Cosmetic Procedures
Background:
- Acne vulgaris affects up to 90% of teenagers, frequently leading to post-acne scars.
- These scars can negatively impact self-esteem and confidence.
Purpose of the Study:
- To evaluate the efficacy of microneedling combined with topical insulin for treating acne scars.
- To compare this combination therapy against simple microneedling.
Main Methods:
- Thirty patients underwent four monthly microneedling sessions.
- One side of the face received microneedling with topical insulin, the other side received simple microneedling.
- Treatment response was assessed using the Acne Scar Assessment Scale.
Main Results:
- Microneedling with insulin resulted in Grade-2 (36.7%) and Grade-3 (63.3%) improvements.
- Simple microneedling led to Grade-0 (33.3%) and Grade-1 (66.6%) improvements.
- The insulin group showed significantly better scar reduction.
Conclusions:
- Microneedling combined with topical insulin is more effective for acne scar treatment.
- This approach presents a potential breakthrough due to insulin's accessibility and low cost.

