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Role of Intralesional Vitamin D3 in the Treatment of Cutaneous Warts
Sabahat Shah1, Seemab Khan1, Noor Us Sabah1
1Department of Dermatology, P.N.S. Shifa Hospital, Karachi, Pakistan.
Objective:
To determine the effect of intralesional vitamin D3 injection in the treatment of cutaneous warts.
Study Design:
Quasi-experimental study. Place and Duration of the Study: Department of Dermatology, P.N.S. Shifa Hospital, Karachi, Pakistan, from May to November 2023.
Methodology:
A total of 30 patients with cutaneous warts of various sizes and durations were selected. Vitamin D3 (0.2 ml, 15 mg/ml) was injected to the base of the warts after anaesthetising with lignocaine (0.2 ml, 20 mg/ml). The injections were repeated two weeks apart for a maximum of 4 sessions or until complete clearance, whichever was earlier. A maximum of two warts were treated per session, and patients were followed up for six months after the last injection.
Results:
The patients' average age was 32.20 ± 11.9 years, and their average illness duration was 14.3 ± 6.5 months. Out of the 30 patients, 10 (33.4%) were females and 20 (66.6%) were males. Twenty cases (66.6%) showed complete clearance, seven cases (23.3%) showed a moderate response, and three (10%) showed a mild response. The only side effects observed in 17 (56.6%) cases were mild swelling and irritation at the injection site, both of which went away on their own within a few days.
Conclusion:
Intralesional vitamin D3 is an effective and affordable treatment option for cutaneous warts.
Key Words:
Cutaneous warts, Common warts, Efficacy, Intralesional treatment, Vitamin D3.
