[Rare multiorgan failure sepsis with Flavonifractor plautii]

Area of Science:

• Medical Microbiology
• Infectious Diseases
• Critical Care Medicine

Background:

• Systemic infections with *Filifactor plautii* (F. plautii) are exceedingly rare.
• Immunocompromised individuals are particularly susceptible to severe sepsis.
• Septic shock necessitates aggressive and immediate medical intervention.

Purpose of the Study:

• To report a rare case of severe septic shock caused by *F. plautii*.
• To discuss the diagnostic challenges and treatment strategies for this unusual infection.
• To highlight the vulnerability of immunocompromised patients to severe sepsis.

Main Methods:

• Case report of a single patient.
• Review of diagnostic procedures and intensive care unit (ICU) management.
• Literature search for previously reported cases of *F. plautii* infection.

Main Results:

• The patient presented with severe septic shock attributed to *F. plautii* systemic infection.
• Invasive diagnostic measures yielded negative findings.
• Treatment involved antibiotics, steroids, and inotropic agents in the ICU.

Conclusions:

• *F. plautii* can cause life-threatening systemic infections, particularly in immunocompromised hosts.
• Early recognition and intensive care are crucial for managing *F. plautii* sepsis.
• This case adds to the limited global understanding of *F. plautii* infections, emphasizing varied clinical presentations.