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Advances in the selective functionalization of B(3,6)-H of o-carboranes
1School of Materials Science and Engineering, Sichuan University of Science & Engineering, Zigong, 643000, P. R. China.
Abstract:
This review summarizes the methodologies for the selective functionalization of the B(3,6) vertices of o-carboranes, including the deboration-capitation reaction, the coupling reaction of B-X (X = I, Br) bonds, reactions of 1,3-dehydro-o-carborane and [3-N2-o-C2B10H11][BF4] as well as transition-metal-catalyzed B-H activation. These works offer a versatile toolbox for synthesizing B(3,6)-substituted o-carborane derivatives and will promote their applications in material science, pharmaceutical chemistry, and related disciplines.
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