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Related Experiment Video

Updated: May 5, 2026

Assessment of Right Ventricular Structure and Function in Mouse Model of Pulmonary Artery Constriction by Transthoracic Echocardiography
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Evaluating Right Ventricular Function Using Longitudinal Displacement.

Marina Leitman1,2, Vladimir Tyomkin1

  • 1Department of Cardiology, Shamir Medical Center, Zerifin 70300, Israel.

Medicina (Kaunas, Lithuania)
|March 27, 2025
PubMed
Summary
This summary is machine-generated.

This study introduces a novel method using longitudinal displacement via speckle-tracking echocardiography to assess right ventricular function. This technique offers a more comprehensive evaluation of global and regional right ventricular function compared to existing methods.

Keywords:
manual measurement of right ventricular strainright ventricular displacementright ventricular function

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Area of Science:

  • Cardiology
  • Medical Imaging
  • Physiology

Background:

  • The right ventricle's complex shape complicates echocardiographic assessment of its function.
  • Existing echocardiographic methods for evaluating right ventricular function have limitations.

Purpose of the Study:

  • To introduce and validate a new method for assessing global and regional right ventricular function using longitudinal displacement.
  • To compare this novel method with existing echocardiographic parameters like tricuspid annulus plane excursion (TAPSE).

Main Methods:

  • Utilized speckle-tracking echocardiography to measure longitudinal displacement in 21 healthy individuals.
  • Analyzed longitudinal displacement across different right ventricular segments (basal, mid, apical).

Main Results:

  • A 'reversed basal-to-apical gradient' was observed in longitudinal displacement.
  • Longitudinal displacement showed strong correlation with TAPSE (89.47% agreement).
  • Longitudinal displacement was higher over the free wall than the septum.

Conclusions:

  • Longitudinal displacement measured by speckle-tracking echocardiography reliably assesses right ventricular function.
  • This method provides a comprehensive segmental assessment, offering advantages over TAPSE.
  • Manual assessment of right ventricular strain is a practical clinical option.