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Related Concept Videos

Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

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Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
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Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

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Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
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Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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Mitral Regurgitation I: Introduction01:20

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Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
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Longitudinal Displacement vs. Strain in Cardiac Amyloidosis: A Speckle Tracking Echocardiography Study.

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Validation of a Manual Method for Measuring Left Atrial Reservoir Strain Against Automated Speckle Tracking Analysis.

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Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
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Inhomogeneity of the Left Atrial Strain.

Marina Leitman1,2, Vladimir Tyomkin1

  • 1Department of Cardiology, Shamir Medical Center, Zerifin 70300, Israel.

Medicina (Kaunas, Lithuania)
|June 27, 2025
PubMed
Summary
This summary is machine-generated.

Left atrial strain, measured by echocardiography, shows significant regional differences in healthy individuals. Strain is highest near the mitral annulus and lowest superiorly, with longitudinal displacement correlating well.

Keywords:
atriumdeformationleft atrial displacementleft atrial functionleft atriumregional left atrial deformationregional left atrial strainstraintriplane left atrial strain

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Area of Science:

  • Cardiology
  • Medical Imaging
  • Echocardiography

Background:

  • Global left atrial strain is standardly assessed via speckle-tracking echocardiography.
  • Regional variations in left atrial strain are not well understood.
  • This study investigates regional left atrial deformation in healthy subjects.

Purpose of the Study:

  • To evaluate regional left atrial deformation in healthy individuals.
  • To map regional differences in left atrial reservoir strain.
  • To assess the correlation between regional strain and longitudinal displacement.

Main Methods:

  • 22 healthy subjects underwent echocardiography.
  • Offline analysis of left atrial reservoir strain from 3-chamber views.
  • Generation of a 3-plane strain map and assessment of regional longitudinal displacement.

Main Results:

  • Biplane and triplane left atrial reservoir strain measurements were comparable.
  • Atrial strain was significantly higher near the mitral annulus than in mid or superior segments.
  • Inferior and septal wall strain exceeded lateral wall strain; longitudinal displacement correlated with strain.

Conclusions:

  • Left atrial strain exhibits significant regional heterogeneity, being highest near the mitral annulus and lowest superiorly.
  • Longitudinal displacement is a valuable complementary metric for assessing left atrial function.
  • Biplane and triplane strain assessments provide similar results for left atrial reservoir strain.