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Approach to the Patient: Hirsutism
Ricardo Azziz1,2,3,4,5, Mina Amiri5, Fernando Bril2
1Department of Obstetrics & Gynecology, Heersink School of Medicine, University of Alabama at Birmingham (UAB), Birmingham, AL 35249, USA.
The Journal of Clinical Endocrinology and Metabolism
|April 9, 2025
Summary
Hirsutism, excess male-pattern hair growth in women, impacts quality of life. Evaluation involves the Ferriman Gallwey scale and addressing causes like PCOS, with treatments including medication and hair removal.
Area of Science:
- Endocrinology
- Dermatology
- Women's Health
Background:
- Hirsutism affects 10% of women globally, causing significant distress and impacting quality of life.
- It is characterized by male-pattern terminal hair growth, influenced by androgens and tissue enzyme activity.
- Diagnosis typically uses the modified Ferriman Gallwey (mFG) scale, with scores >4-6 often indicating hirsutism.
Purpose of the Study:
- To provide a comprehensive overview of hirsutism, including its causes, diagnosis, and management.
- To emphasize the importance of evaluating underlying conditions and patient distress.
- To outline current therapeutic strategies for hirsutism.
Main Methods:
- Review of established diagnostic criteria and scales for hirsutism.
- Discussion of the etiological factors contributing to hirsutism.
- Summary of available medical and mechanical treatment options.
Main Results:
- Hirsutism is most commonly associated with Polycystic Ovary Syndrome (PCOS) in 80-90% of cases.
- Other causes include idiopathic hirsutism, non-classic adrenal hyperplasia, and rarer conditions like neoplasms and endocrine disorders.
- Effective management often requires a combination of therapies tailored to individual needs.
Conclusions:
- Hirsutism necessitates thorough evaluation to identify underlying causes, regardless of visible severity.
- Treatment strategies should be individualized, considering symptom severity, reproductive desires, and patient preferences.
- A combined therapeutic approach, incorporating medical and mechanical methods with shared decision-making, offers the most effective management.
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