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Related Concept Videos

Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

97
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
97
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

128
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
128
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

316
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
316
Peptic Ulcer Disease I: Introduction01:30

Peptic Ulcer Disease I: Introduction

103
Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
103
Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

98
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
98
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

64
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
64

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Related Experiment Video

Updated: May 11, 2025

Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E
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Unveiling the Uncommon: Pyoderma Gangrenosum as an Extraintestinal Complication of Ulcerative Colitis.

Caleb Glover1, Ali Rida1, Eric Nguyen1

  • 1McLaren-Greater Lansing Hospital, Lansing, MN.

ACG Case Reports Journal
|April 17, 2025
PubMed
Summary

Pyoderma gangrenosum (PG), a rare inflammatory skin condition, can manifest as abdominal ulcers in ulcerative colitis patients. Early diagnosis and treatment with steroids and infliximab are crucial for better outcomes.

Area of Science:

  • Dermatology
  • Gastroenterology
  • Immunology

Background:

  • Pyoderma gangrenosum (PG) is a rare, neutrophil-driven inflammatory skin disorder.
Keywords:
inflammatory bowel diseasepyoderma gangrenosumulcerative colitis

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  • PG is the second most common dermatologic manifestation of inflammatory bowel disease (IBD), affecting less than 1% of IBD patients.
  • Abdominal PG as an extraintestinal manifestation of ulcerative colitis (UC) is particularly rare.