Angiofibroma arising from the olfactory epithelium.

Area of Science:

• Otorhinolaryngology
• Pathology
• Surgical Oncology

Background:

• Angiofibromas are rare benign vascular tumors.
• Juvenile nasopharyngeal angiofibroma (JNA) is the most common type.
• Extranasopharyngeal angiofibromas (ENAs) are rare, distinct entities outside the nasopharynx.

Purpose of the Study:

• To present a case of extranasopharyngeal angiofibroma (ENA).
• To highlight the unique clinical and histopathological features of ENAs.
• To discuss the diagnostic and management considerations for ENAs.

Main Methods:

• Case report of a 42-year-old male with epistaxis and nasal obstruction.
• Diagnostic imaging: Computed Tomography and Magnetic Resonance Imaging.
• Surgical resection via endoscopic endonasal approach followed by histopathological and immunohistochemical analysis.

Main Results:

• Imaging revealed an expansile solid lesion in the right nasal cavity.
• Tumor insertion into the olfactory epithelium was noted.
• Histopathology confirmed angiofibroma, consistent with ENA.

Conclusions:

• ENAs can affect all age groups and genders.
• ENAs are typically less vascularized and more rapidly growing than JNAs.
• Early diagnosis and complete surgical resection of ENAs lead to favorable outcomes with low recurrence.