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COVID-19-Related Diplopia and Its Treatment
Shannon Patricia1, Antonia Kartika2,3, Irma Melyani Puspitasari4,5
1Bachelor Program in Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang 45363, West Java, Indonesia.
Medicina (Kaunas, Lithuania)
|April 26, 2025
Summary
COVID-19 can cause diplopia, a vision condition where one sees double. This review summarizes COVID-19 related diplopia cases and their treatments over five years, finding most patients recovered.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Neurology
Background:
- COVID-19 disease and vaccination are associated with various complications, including ocular manifestations.
- Diplopia, or double vision, is a reported complication linked to SARS-CoV-2 infection and its management.
- Understanding the spectrum of COVID-19-induced diplopia is crucial for timely diagnosis and treatment.
Purpose of the Study:
- To review and summarize cases of diplopia associated with COVID-19 over the past five years.
- To identify common diagnostic methods and treatments for COVID-19-related diplopia.
- To analyze the recovery patterns and symptom variations in patients experiencing diplopia due to COVID-19.
Main Methods:
- A comprehensive literature search was conducted using PubMed and Scopus databases.
- Keywords included "diplopia," "COVID-19," and "treatment" to identify relevant studies.
- Sixteen articles, primarily case reports, were selected and analyzed based on predefined inclusion criteria.
Main Results:
- Diplopia cases linked to COVID-19 were reported globally across America, Europe, Asia, and Africa.
- A total of 26 patients aged 14-81 were included, with symptoms varying based on vaccination status, infection, or post-infection.
- Common diagnostic tools included MRI, CT scans, and various ophthalmological examinations.
Conclusions:
- Most patients with COVID-19-related diplopia recovered within 1 day to 8 months.
- Corticosteroids (prednisone, methylprednisolone, prednisolone) were the primary treatment, often supplemented with other medications and supportive care like eye patches.
- Distinct symptom profiles were observed in patients experiencing diplopia following vaccination, during infection, or post-infection.
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