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CO-OCCURRENCE OF HANTAVIRUS PULMONARY SYNDROME AND HEMORRHAGIC FEVER WITH RENAL SYNDROME
M Zhamutashvili1, T Gognadze2, N Jojua2
11European University, Tbilisi; 2Infectious Diseases, AIDS and Clinical Immunology Research Center, Georgia.
Abstract:
Hantavirus infections can manifest as two distinct clinical syndromes: Hantavirus Pulmonary Syndrome (HPS) and Hemorrhagic Fever with Renal Syndrome (HFRS). We present a rare case of a 36-year-old male patient who simultaneously developed both syndromes following exposure to Hantavirus. The patient presented with fever, headache, diarrhea, blurred vision, petechial rash, and oliguria. Laboratory findings revealed severe thrombocytopenia, leukocytosis with bandemia, elevated CRP, and increased creatinine levels. The patient subsequently developed pneumonia and acute kidney failure. Initially suspected as Crimean-Congo hemorrhagic fever due to endemic geographic considerations, the diagnosis of Hantavirus infection was confirmed by RT-PCR. This case highlights the importance of considering Hantavirus in the differential diagnosis of patients presenting with both pulmonary and renal manifestations, especially in endemic areas, and emphasizes the need for improved diagnostic techniques in developing countries.
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