[Transition in patients with cystic fibrosis and asthma]

Adolescence represents a period of significant transformation for individuals with chronic conditions such as cystic fibrosis (CF) and asthma. Due to substantial progress in highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapy, nearly everyone with CF now reaches adulthood, necessitating ongoing interdisciplinary medical care. Conversely, approximately 70% of children with asthma experience a resolution of symptoms as they reach adulthood. Factors contributing to the persistence of asthma into adulthood include the presence of severe asthma, diminished lung function in childhood and allergic comorbidities. Especially for young adults with severe asthma, continuous pneumological care including uninterrupted access to biologics, must be provided. During the transition process, considerations regarding career choices are pertinent for both patient groups. Additionally, issues related to family planning and prenatal diagnostics become particularly relevant for young adults with CF and should be addressed during the transition process. In both patient groups, an early and structured initiation of the transition process is essential. The use of checklists and transition plans can facilitate the transfer of critical information and ensure a seamless transition. Joint pediatric and internal medicine consultations foster trust and ensure medical quality. Ultimately, a successful transition should enable individuals with CF as well as those with asthma to assume responsibility for their condition and treatment, recognize clinical deterioration, and seek timely assistance.