[Chronic arterial hypertension in children with corrected obstructive uropathy]

Area of Science:

• Pediatric Nephrology
• Urology

Background:

• Obstructive uropathy in children can lead to chronic hypertension.
• Hypertension may persist despite successful urinary flow restoration.

Observation:

• This report details three pediatric cases of obstructive uropathy with severe hypertension.
• Hypertension manifested up to six years post-urinary flow normalization.
• Elevated serum renin levels were observed in two patients.

Findings:

• Kidney parenchymal damage is the likely cause of hypertension in these cases.
• Glomerular filtration rate was reduced in all affected children.
• Further decline in kidney function was prevented in two patients over 3-4 years.

Implications:

• Early hypertension detection and management are crucial for children with obstructive uropathy.
• Understanding the link between obstructive uropathy, kidney damage, and hypertension is vital.
• This highlights the long-term renal and cardiovascular risks associated with obstructive uropathy.